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Effects of ethanol, naltrexone, nicotine and varenicline in an ethanol and nicotine co-use model in Sprague-Dawley rats.

Author
Abstract
:

As alcohol and nicotine use disorders are entwined, it may be possible to develop a single medication to treat both. We previously developed a model for ethanol (EtOH) and nicotine co-use in female selectively bred alcohol-preferring (P) rats. To model co-use in a genetically diverse population, we adapted the model to outbred Sprague-Dawley rats of both sexes and assessed the effect of drug pretreatments.

Year of Publication
:
2020
Journal
:
Drug and alcohol dependence
Volume
:
212
Number of Pages
:
107988
Date Published
:
2020
ISSN Number
:
0376-8716
URL
:
https://linkinghub.elsevier.com/retrieve/pii/S0376-8716(20)30153-8
DOI
:
10.1016/j.drugalcdep.2020.107988
Short Title
:
Drug Alcohol Depend
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